Synthetic glycopeptides and glycoproteins with applications in biological research

• Ulrika Westerlind

Beilstein J. Org. Chem. 2012, 8, 804–818, doi:10.3762/bjoc.8.90

• backbones, or mimics thereof, offer further possibilities to study protein-binding events. Keywords: glycopeptide binding; glycopeptides; glycoprotein synthesis; solid-phase peptide synthesis; synthetic vaccines; Introduction The majority of human proteins are co- or post-translationally modified by mono

• mutant or a high-mannose oxazoline donor and an Endo-A mutant, two different homogenous glycoproteins 40 and 41 were formed (Scheme 7) [87]. Glycopeptide binding events Carbohydrates on proteins and lipids play critical roles in cell–cell and cell–external-agent binding events. Efforts in the preparation